Covid-19 induced avascular necrosis in maxilla - a rare case report

Authors

  • Gaurav Gupta Wisdom Dental Clinics

DOI:

https://doi.org/10.52977/ujmfs.2021.1.2.13

Keywords:

Covid-19, Mucormycosis, Sars Cov2, necrosis of maxilla, Aspergillosis

Abstract

COVID-19  has emerged as a challenge to the clinicians worldwide. Since the outbreak in December 2019, COVID-19 has affected >11,301,800 people (World Health Organization 2020b). (1) The most common symptoms are fever and dry cough and in few cases shortness of breath, dysosmia, and dysgeusia. Present understanding among researchers shows that coronavirus invades human cells via the receptor angiotensin-converting enzyme 2 (ACE2) through scRNA-seq data analyses. The prevalence of clinical manifestations is still unknown, the range of COVID-19 manifestations on the oral cavity has been considered of broad. The current case aims to report a rare finding of bone and soft tissue defect in maxilla as a possible sequelae of C0VID-19 infection.

References

Chen, N, Zhou, M, Dong, X, Qu, J, Gong, F, Han, Y, Qiu, Y, Wang, J, Liu, Y, Wei, Y, et al. 2020. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 395(10223):507–513.

Guan, W, Ni, Z, Hu, Y, Liang, W, Ou, C, He, J, Liu, L, Shan, H, Lei, C, Huiet, DSC, et al.;

China Medical Treatment Expert Group for COVID-19 . 2020. Clinical characteristics

of coronavirus disease 2019 in China. N Engl J Med. 382(18):1708–1720.

Atkins, D, Eccles, M, Flottorp, S, Guyatt, GH, Henry, D, Hill, S, Liberati, A, O’Connell, D, Oxman, AD, Phillips, B, et al.; GRADE Working Group . 2004. Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches. BMC Health Serv Res. 4(1):38.

Amorim dos Santos J, Normando AGC, Carvalho da Silva RL, et al. Oral Manifestations in Patients with COVID-19: A Living Systematic Review. Journal of Dental Research. September 2020.

Zou, X, Chen, K, Zou, J, Han, P, Hao, J, Han, Z. 2020. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med. 14(2):185–192.

Wang, C, Wu, H, Ding, X, Ji, H, Jiao, P, Song, H, Li, S, Dua, H. 2020. Does infection of 2019 novel coronavirus cause acute and/or chronic sialadenitis? Med Hypotheses. 140:109789.

Xu, J, Li, Y, Gan, F, Du, Y, Yao, Y. 2020. Salivary glands: potential reservoirs for COVID-19 asymptomatic infection. J Dent Res. 99(8):989.

Mariz, BALA, Brandão, TB, Ribeiro, ACP, Lopes, MA, Santos-Silva, AR. 2020. New insights for the pathogenesis of COVID-19-related dysgeusia. J Dent Res [epub ahead of print 12 Jun 2020].

Godinho, GV, Paz, ALLM, de Araújo Gomes, EPA, Garcia, CL, Volpato, LER. 2020. Extensive hard palate hyperpigmentation associated with chloroquine use. Br J Clin Pharmacol [epub ahead of print 20 Apr 2020]

Cox, MJ, Loman, N, Bogaert, D, O’Grady, J. 2020. Co-infections: potentially lethal and unexplored in COVID-19. Lancet Microbe. 1(1):e11.

Dziedzic, A, Wojtyczka, R. 2020. The impact of coronavirus infectious disease 19 (COVID-19) on oral health. Oral Dis [epub ahead of print 18 Apr 2020]. doi:10.1111/odi.13359

Gupta, A.; Madhavan, M.V.; Sehgal, K.; Nair, N.; Mahajan, S.; Sehrawat, T.S.; Bikdeli, B.; Ahluwalia, N.; Ausiello, J.C.; Wan, E.Y.; et al. Extrapulmonary manifestations of COVID-19. Nat. Med. 2020, 26, 1017–1032.

Lenti, M.V.; Borrelli de Andreis, F.; Pellegrino, I.; Klersy, C.; Merli, S.; Miceli, E.; Aronico, N.; Mengoli, C.; Di Stefano, M.; Cococcia, S.; et al. Impact of COVID-19 on liver function: Results from an internal medicine unit in Northern Italy. Intern. Emerg. Med. 2020.

Pedrosa, M.; Sipert, C.R.; Nogueira, F.N. Salivary Glands, Saliva and Oral Presentations in COVID-19 infection. SciELO 2020

Herrera, D.; Serrano, J.; Roldán, S.; Sanz, M. Is the oral cavity relevant in SARS-CoV-2 pandemic?Clin. Oral Investig. 2020, 24, 2925–2930.

Tan, E.C.K.; Lexomboon, D.; Sandborgh-Englund, G.; Haasum, Y.; Johnell, K. Medications That Cause Dry Mouth as an Adverse Effect in Older People: A Systematic Review and Metaanalysis. J. Am. Geriatr. Soc. 2018, 66, 76–84

López-Pintor, R.M.; Casañas, E.; González-Serrano, J.; Serrano, J.; Ramírez, L.; de Arriba, L.; Hernández, G. Xerostomia, Hyposalivation, and Salivary Flow in Diabetes Patients. J. Diabetes Res. 2016, 2016, 4372852.

Sinjari, B.; Feragalli, B.; Cornelli, U.; Belcaro, G.; Vitacolonna, E.; Santilli, M.; Rexhepi, I.; D’Addazio, G.; Zuccari, F.; Caputi, S. Artificial Saliva in Diabetic Xerostomia (ASDIX): Double Blind Trial of Aldiamed® Versus Placebo. J. Clin. Med. 2020, 9, 2196

Richardson, S.; Hirsch, J.S.; Narasimhan, M.; Crawford, J.M.; McGinn, T.; Davidson, K.W.; The Northwell COVID-19 Research Consortium; Barnaby, D.P.; Becker, L.B.; Chelico, J.D.; et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA 2020, 323, 2052–2059.

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Published

2021-09-26

How to Cite

Gupta, G. (2021). Covid-19 induced avascular necrosis in maxilla - a rare case report. UNIVERSITY JOURNAL MAXILLOFACIAL SURGERY AND ORAL SCIENCES, 1(2). https://doi.org/10.52977/ujmfs.2021.1.2.13